https://medicalxpress.com/news/2021-11-uncovers-ge
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researchers have identified the gene responsible for doubling the risk of respiratory failure from COVID-19.
gene LZTFL1 causes the effect
The researchers found that the higher risk version of the gene probably prevents the cells lining airways and the lungs from responding to the virus properly.
We found that the increased risk is not because of a difference in gene coding for a protein, but because of a difference in the DNA that makes a switch to turn a gene on.
Sixty percent of people with South Asian ancestry carried this higher-risk version of the gene compared to 15 percent of those with European ancestry—explaining in part the higher death rates and hospitalisations in the former group. The study also found that 2 percent of people with Afro-Caribbean ancestry carried the higher risk genotype