Polio and SARS2, and Smallpox, HIV, and most other classes of viruses are vastly different from each other.. odds that there will ever be One Vaccine for Flu or now SARS2 is unlikely, it's not polio. It's not the vaccines' faults. N-proteins aren't The Answer, for several reasons. They're A target, not really the best target. They're far from static as well. None of the virus is.