What is the assay in question? Receptor occupancy
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What is the assay in question? Receptor occupancy seems like an obvious choice. Can that be done retroactively? I'm skeptical if it means rounding up former trial participants but maybe there is a workaround.
If it is RO they wouldn't need past trial participants. They could use any HAART patients to determine occupancy at each dosage and correlate that to viral load outcomes from the trial.