Jlang, We have discussed (and you dismissed) th
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Posted On: 08/31/2021 6:25:42 AM
Jlang,
We have discussed (and you dismissed) the intrinsic rates of mutation amongst the various classes of viruses. Mutations are, in simple terms, a function of mutation rates x number of infected x duration of viral replication.
Undoubtedly, untreated/immunosuppressive HIV patients have persistent replication, but so does anyone one else with a poorly functioning immune system who fails to die quickly from Covid.
Cancers, MS, RA etc.
Larger picture, even the non-immune suppressed by dint of sheer numbers produce variants of concern - witness India.
Immune suppression undoubtedly increases the opportunity for variants development, but so does the infections of more than 200M people without previous immune compromise.
We have discussed (and you dismissed) the intrinsic rates of mutation amongst the various classes of viruses. Mutations are, in simple terms, a function of mutation rates x number of infected x duration of viral replication.
Undoubtedly, untreated/immunosuppressive HIV patients have persistent replication, but so does anyone one else with a poorly functioning immune system who fails to die quickly from Covid.
Cancers, MS, RA etc.
Larger picture, even the non-immune suppressed by dint of sheer numbers produce variants of concern - witness India.
Immune suppression undoubtedly increases the opportunity for variants development, but so does the infections of more than 200M people without previous immune compromise.
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