Crashco, here's the link to the article you reques

Crashco, here's the link to the article you requested:

https://internal-journal.frontiersin.org/arti...20806/full

Brilacidin is mentioned in the last paragraph, as noted by Rip Van 03 in the post preceding mine:

"Several conventional therapeutic drugs, including but not limited to antimalarial drugs, protease inhibitors, renin–angiotensin system (RAS) inhibitors, inhibitors of the RNA-dependent RNA polymerase, and immune suppressants, are being repurposed for the treatment of COVID-19 (Khavinson et al., 2020; Spaccarotella et al., 2021). However, peptide-based therapeutic drugs including AMPs are sometimes a better choice than conventional drugs due to their higher efficacy, lower molecular weight, and lower toxicity and side effects (Castel et al., 2011). Among peptide-based therapeutic drugs, AMP-related small peptide derivatives (Zhao et al., 2020) and non-peptide mimetics (Bakovic et al., 2020) are emerging as promising drug candidates. Several potential SARS-CoV-2 entry inhibitor peptides, and strategies used to design those peptides targeting the ACE2 receptor or the viral spike protein and its activating proteases, have been outlined in a recent review by Schütz et al. (2020). Additionally, peptoid mimics (sequence-specific N-substituted glycine oligomers) of AMPs and an antimicrobial DP7 peptide (VQWRIRVAVIRK) were recently shown to have anti-CoV-2 activity (Zhang R. et al., 2021; Diamond et al., 2021). Moreover, a synthetic mimetic of defensins, Brilacidin, has been shown to potently inhibit CoV-2 in an ACE2-positive human lung cell line (Bakovic et al., 2021) and recently received approval by the Federal Drug Administration (FDA) to start a phase 2 clinical trial in COVID-19 patients (ClinicalTrials.gov; Identifier: NCT04784897)."