Many sc meds are weight dependent, but I'm not sur

Many sc meds are weight dependent, but I'm not sure why LL is administered that way (other than the fact that it is very safe/non toxic). I'm not aware of any reason a clinician would assume that a 105lb woman would need 15mg/kg while a heavier person would only need 7.5mg/kg. While endless RO studies might lead to some different answers(based on many up regulation/down regulation conditions or even differences between male and female biochemistry similar to alcohol dehydrogenase levels), I'm not aware of any info/papers about LL that answers that. Good question though, IMO.