Naturally my next question is will this be curativ
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Naturally my next question is will this be curative or a periodic therapy?
I've been pondering that one for quite awhile. Il-4 and IL-6 (both CCR5 regulated) can contribute to hyperactivity in B cells. Downregulation of both by leronlimab might possibly restore normal B cell production. We won't know until trials (possibly longer) are completed.
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The autoimmune aspect is disturbing in that it might have the potential to be fatal/disabling - your thoughts?
We know that longhaulers is quite often disabling I would think any near term fatalities would be rare but it could significantly shorten lifespan.