The time differentials are certainly an unknown factor. Anecdotal testimony has indicated, That SC has an effect within a few short hours. Perhaps IV should be reserved for only the most severe cases. These are issues to be dealt with as actual practitioners gain practical experience with the drug over the years, not another trial to determine efficacy. We don't have the luxury of years. What we do have is government functionaries in ivory towers playing dominos while the world is at risk.