I wonder how many patients oxygen level was back o
Post# of 154851
(Total Views: 552)
Posted On: 03/30/2021 9:44:59 AM
I wonder how many patients oxygen level was back over 94% at day 14 and 28 .. Seems like the important metric since your oxy needed to be below that level to be included . Just compare that percentage to placebo . Sorry simple when you think about it . But no , they tout all this other bs . What happened to simple thinking in this world ??
“””””The trial enrolled 520 patients who had their experience blood oxygen saturation (SpO2) less than or equal to 94%, or needed some sort of non-invasive oxygen and were also hospitalized. Initially the studies primary endpoint was incidence of IMV and 28 day mortality, but that was changed after and interim analysis by the DSMC to Ventilator-free Survival at Day 28 so that the trial could meet its primary endpoint. They also bumped up enrollment to meet this endpoint, but not enough to power the study for mortality. Like many studies before them they saw a “favorable trend” in mortality of 9.6% versus 13.9% in the placebo arm but there was no mortality benefit. They also did well in terms of safety and no new SAE’s were observed or attributable to lenzilumab.””
“””””The trial enrolled 520 patients who had their experience blood oxygen saturation (SpO2) less than or equal to 94%, or needed some sort of non-invasive oxygen and were also hospitalized. Initially the studies primary endpoint was incidence of IMV and 28 day mortality, but that was changed after and interim analysis by the DSMC to Ventilator-free Survival at Day 28 so that the trial could meet its primary endpoint. They also bumped up enrollment to meet this endpoint, but not enough to power the study for mortality. Like many studies before them they saw a “favorable trend” in mortality of 9.6% versus 13.9% in the placebo arm but there was no mortality benefit. They also did well in terms of safety and no new SAE’s were observed or attributable to lenzilumab.””
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