Good point. Lots of things to consider why those

Good point. Lots of things to consider why those 75 did not receive any other "standard" treatment for their Covid besides leronlimab, which means no steroids and no remdesivir. I'm wondering if these were patients with organ failure or immunocompromised, and really nothing much was able to be given to them and nothing was going to help them? If that were true though, then one would expect placebo outcomes to be much worse for them too. It's possible those patients were really bad off and somehow LL made them worse. I wonder too if those patients got really bad care, if the systems were overwhelmed, and somehow LL made them worse.

The other option is that it was random bad luck and not meaningful. Larger numbers would have given us more confidence in the outcome.

It would be good to try to learn more about why those 75 seemed to have worse outcomes on LL versus placebo, agree. Maybe there is a biomarker, or certain medical condition (say kidney failure, for instance) where one definitely doesn't want to use LL. I hope they look into it.