Thx crashco. I suspect the critically low blood ox
Post# of 72447
(Total Views: 316)
Posted On: 02/27/2021 8:44:16 PM
Thx crashco. I suspect the critically low blood oxygen levels are due to the gunk (ground-glass effect shown in x-rays) in lungs. As you said, there's nothing on the internet re the virus infecting red blood cells. That would have been disastrous.
I included info re ZyeSamir for informational purposes in the prior post, but I have to say that I am not clear how it works. The literature says simply that ZyeSamir prevents virus replication. There's no evidence it kills the virus, unlike Brilacidin. I am not even sure there were lab tests to investigate ZyeSamir's mechanism against Covid-19.
Given the low bar set by the EUA for Remdesirvir, I am hoping that showing significantly reduced hospital stays for moderate patients would be sufficient for an EUA for Brilacidin. I think the expectation is high for that case. What I am not sure about is reduced hospital stays for severe patients. Given that they may have blood clots, blood vessel and organ damage - definitely lung issues - even if Brilacidin clears out the virus I wonder if there would be a statistically significant difference in reduced hospital stays by 28D for severe patients given the improvement in SOC since early 2020. But this may not be a particularly relevant outcome to Leo. I do wish that Leo went for 60D monitoring instead of just 28D, but he may have to conserve his resources.
I included info re ZyeSamir for informational purposes in the prior post, but I have to say that I am not clear how it works. The literature says simply that ZyeSamir prevents virus replication. There's no evidence it kills the virus, unlike Brilacidin. I am not even sure there were lab tests to investigate ZyeSamir's mechanism against Covid-19.
Given the low bar set by the EUA for Remdesirvir, I am hoping that showing significantly reduced hospital stays for moderate patients would be sufficient for an EUA for Brilacidin. I think the expectation is high for that case. What I am not sure about is reduced hospital stays for severe patients. Given that they may have blood clots, blood vessel and organ damage - definitely lung issues - even if Brilacidin clears out the virus I wonder if there would be a statistically significant difference in reduced hospital stays by 28D for severe patients given the improvement in SOC since early 2020. But this may not be a particularly relevant outcome to Leo. I do wish that Leo went for 60D monitoring instead of just 28D, but he may have to conserve his resources.
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