NEW 1. Loss of MANF causes childhood onset syndrom
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Posted On: 02/06/2021 2:43:41 PM
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NEW 1. Loss of MANF causes childhood onset syndromic diabetes due to increased endoplasmic reticulum stress
Diabetes. 2021 Jan 26;db201174. doi: 10.2337/db20-1174.
"By describing a new form of monogenic neurodevelopmental diabetes syndrome caused by disturbed ER function, we highlight the importance of adequate ER stress regulation for proper human beta cell function and demonstrate the crucial role of MANF in this process."
https://pubmed.ncbi.nlm.nih.gov/33500254/
Diabetes. 2021 Jan 26;db201174. doi: 10.2337/db20-1174.
"By describing a new form of monogenic neurodevelopmental diabetes syndrome caused by disturbed ER function, we highlight the importance of adequate ER stress regulation for proper human beta cell function and demonstrate the crucial role of MANF in this process."
https://pubmed.ncbi.nlm.nih.gov/33500254/
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