COVID-19 Attack On Brain, Not Lungs, Triggers Seve
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Posted On: 01/25/2021 11:22:36 AM
COVID-19 Attack On Brain, Not Lungs, Triggers Severe Disease In Mice
I don't remember seeing this posted here - apologies if this is a duplicate.
Note that this is a study in mice. Leronlimab's crossing the blood - brain barrier looks bigger and bigger for Covid, not just indications down the road.
Highlights below.
Georgia State University biology researchers have found that infecting the nasal passages of mice with the virus that causes COVID-19 led to a rapid, escalating attack on the brain that triggered severe illness, even after the lungs were successfully clearing themselves of the virus.
Assistant professor Mukesh Kumar, the study’s lead researcher, said the findings have implications for understanding the wide range in symptoms and severity of illness among humans who are infected by SARS-CoV-2, the virus that causes COVID-19.
“Our thinking that it’s more of a respiratory disease is not necessarily true,” Kumar said. “Once it infects the brain it can affect anything because the brain is controlling your lungs, the heart, everything. The brain is a very sensitive organ. It’s the central processor for everything.”
Kumar said that early in the pandemic, studies involving mice focused on the animals’ lungs and did not assess whether the virus had invaded the brain. Kumars’ team found that virus levels in the lungs of infected mice peaked three days after infection, then began to decline. However, very high levels of infectious virus were found in the brains of all the affected mice on the fifth and sixth days, which is when symptoms of severe disease became obvious, including labored breathing, disorientation and weakness.
https://neurosciencenews.com/covid-19-brain-17609/
I don't remember seeing this posted here - apologies if this is a duplicate.
Note that this is a study in mice. Leronlimab's crossing the blood - brain barrier looks bigger and bigger for Covid, not just indications down the road.
Highlights below.
Georgia State University biology researchers have found that infecting the nasal passages of mice with the virus that causes COVID-19 led to a rapid, escalating attack on the brain that triggered severe illness, even after the lungs were successfully clearing themselves of the virus.
Assistant professor Mukesh Kumar, the study’s lead researcher, said the findings have implications for understanding the wide range in symptoms and severity of illness among humans who are infected by SARS-CoV-2, the virus that causes COVID-19.
“Our thinking that it’s more of a respiratory disease is not necessarily true,” Kumar said. “Once it infects the brain it can affect anything because the brain is controlling your lungs, the heart, everything. The brain is a very sensitive organ. It’s the central processor for everything.”
Kumar said that early in the pandemic, studies involving mice focused on the animals’ lungs and did not assess whether the virus had invaded the brain. Kumars’ team found that virus levels in the lungs of infected mice peaked three days after infection, then began to decline. However, very high levels of infectious virus were found in the brains of all the affected mice on the fifth and sixth days, which is when symptoms of severe disease became obvious, including labored breathing, disorientation and weakness.
https://neurosciencenews.com/covid-19-brain-17609/
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