Perhaps he doesn't have a vested interest/axe to grind with HGEN....could you explain this matter of end-point shopping....on the surface, it feels like circumvention/cheating.moving the goalpost...with all of these trials SO completely regulated..how is it you are permitted to change the markers realizing you won't hit your original intention?..this is not clear to me...and why would a regulatory body allow this to happen....feels like a hand under the wire instead of the head.