You pose a logical question.. has a lot of merit.....But to define the efficacy of any drug...and it's behavior etc... you need comparative clinical evidence......hence the CD12...we have anecdotal evidence coming out of our A$$...No one cares......sometimes in life, ...people have to be martyred to give any drug the necessary gravitas....to be adopted by the medical community and lastly dosed to the public.....personally I am in the early age group of subjective martyrs......better us than Children.....the FDA doesn't care about the available pool..they want results.