My theory is that full immunity is achieved only b
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Posted On: 01/13/2021 6:34:13 PM
My theory is that full immunity is achieved only by a homozygous double mutant just the same as HIV.
The Brazil study earlier in this thread suggests the natural covid immunity reduces the frequency of heterozygous mutants found in a trial to roughly half of the frequency in the general population.
In the Brazil study, 10% of the covid sick patients were heterozygous.
So 10% times CD12's 394 yields about 40 heterozygotes in CD12.
But maybe Cdiddy is right, the natural immunity of heterozygotes is even better and its only 20 or 10 or 5 heterozygotes in the CD12 trial.
But lower numbers of heterozygotes in CD12 is not a discouragement for genotyping, its a massive encouragement because it suggests that maybe if the RO is high enough then the natural immunity is recapitulated by leronlimab.
If I genotype covid patients and I find fewer CCR5delta32 than I expect then I am encouraged to look very hard, and very quickly, at ways to increase the RO by increasing the dose and going intravenous.
The Brazil study earlier in this thread suggests the natural covid immunity reduces the frequency of heterozygous mutants found in a trial to roughly half of the frequency in the general population.
In the Brazil study, 10% of the covid sick patients were heterozygous.
So 10% times CD12's 394 yields about 40 heterozygotes in CD12.
But maybe Cdiddy is right, the natural immunity of heterozygotes is even better and its only 20 or 10 or 5 heterozygotes in the CD12 trial.
But lower numbers of heterozygotes in CD12 is not a discouragement for genotyping, its a massive encouragement because it suggests that maybe if the RO is high enough then the natural immunity is recapitulated by leronlimab.
If I genotype covid patients and I find fewer CCR5delta32 than I expect then I am encouraged to look very hard, and very quickly, at ways to increase the RO by increasing the dose and going intravenous.
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