Anyone know details of NEWS2? I'm wondering if
Post# of 148185
(Total Views: 440)
Posted On: 01/02/2021 9:27:14 PM
Anyone know details of NEWS2?
I'm wondering if there is a cutoff indicating a low-flow oxygen user is about to go high flow - translated, become severe - with say, 70% odds?
Knowing the supply of leronlimab will be constrained, I'm guessing that's the point to administer it. Soon enough to avoid much of the damage of the disease but late enough keep the "number needed to treat" - to prevent a death - low.
It's likely a bit earlier than what would be be OK under an EUA. Thoughts?
Remember, we do have change in the seven-point ordinal scale (death, intub, hi flo, lo flo, no o2 but hosp, home/restr, home/no restr) as a secondary endpoint. With sig on primary, we'll be able to show the progression of sub-groups as a visual story.
I'm wondering if there is a cutoff indicating a low-flow oxygen user is about to go high flow - translated, become severe - with say, 70% odds?
Knowing the supply of leronlimab will be constrained, I'm guessing that's the point to administer it. Soon enough to avoid much of the damage of the disease but late enough keep the "number needed to treat" - to prevent a death - low.
It's likely a bit earlier than what would be be OK under an EUA. Thoughts?
Remember, we do have change in the seven-point ordinal scale (death, intub, hi flo, lo flo, no o2 but hosp, home/restr, home/no restr) as a secondary endpoint. With sig on primary, we'll be able to show the progression of sub-groups as a visual story.
(2)
(0)CytoDyn Inc (CYDY) Stock Research Links
Scroll down for more posts ▼