Something we seem to have forgotten: our primary
Post# of 155038
(Total Views: 732)
Posted On: 10/25/2020 3:43:40 PM
Something we seem to have forgotten: our primary end-point is still death at 28 days.
This is VERY, VERY ballsy to put it some way.
Remdesivir failed miserably both, here and overseas. Which would indicate that either does not work or does little. Never mind FDA approved for hospitalized patients. Everybody agrees it does not prevent deaths:
So, why is this an important fact?? Well, we little "nonexistent" company are trying to prove our drug can reduce deaths (the ultimate benefit). This would mean benefit for all those in hospital, severe and critical.
Meaning is better than Remdesivir by far!!!
Does it take cojones to attempt something like this ?? You bet.
Why did we believe that we had them ?? Well, because we think our drug damn works.
Was it wise ?? Well... maybe hospitalization days reduction would have been a much easier goal ... but we are not shrinking violets ... are we ???
So, what is the point??? The point is that Remdesivir is NOT competition for us. They can't claim they can reduce the death rate; if we do they can't claim they can replace us.
We can.
We will be there at the mountain top looking downwards.... and comprehending we were the ones that conquered it.
This is VERY, VERY ballsy to put it some way.
Remdesivir failed miserably both, here and overseas. Which would indicate that either does not work or does little. Never mind FDA approved for hospitalized patients. Everybody agrees it does not prevent deaths:
Quote:
This absolutely excludes the suggestion that Remdesivir can prevent a substantial fraction of all deaths. The confidence interval is comfortably compatible with prevention of a small fraction of all deaths, but is also comfortably compatible with prevention of no deaths (which would be consistent with the apparent lack of any reduction by Remdesivir in the initiation of ventilation or the duration of hospitalization in Solidarity).
So, why is this an important fact?? Well, we little "nonexistent" company are trying to prove our drug can reduce deaths (the ultimate benefit). This would mean benefit for all those in hospital, severe and critical.
Meaning is better than Remdesivir by far!!!
Does it take cojones to attempt something like this ?? You bet.
Why did we believe that we had them ?? Well, because we think our drug damn works.
Was it wise ?? Well... maybe hospitalization days reduction would have been a much easier goal ... but we are not shrinking violets ... are we ???
So, what is the point??? The point is that Remdesivir is NOT competition for us. They can't claim they can reduce the death rate; if we do they can't claim they can replace us.
We can.
We will be there at the mountain top looking downwards.... and comprehending we were the ones that conquered it.
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