Respert wrote about a Severe trial for another dru
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Posted On: 10/13/2020 9:12:33 AM
Respert wrote about a Severe trial for another drug:
Yes, if 83% of the 65 patients in the placebo/SOC arm died, that would have been 54 deaths. Since we know the total mortality was 45 deaths for the entire trial, that would indicate mortality of approximately -9 patients in the Leron arm, that is to say, 9 Leron patients became immortal. In other words, almost 7 percent of the Leron arm attained immortality. The immortality p-value, however, does not reach statistical significance, so the FDA would not approve on this basis.
Quote:
Only 17% were alive after 60 days out of 24 patients, apparently. Now, if you’re feeling optimistic like I said, consider how many of the 65 or so placebo patients in our trial would have passed away at that same rate
Yes, if 83% of the 65 patients in the placebo/SOC arm died, that would have been 54 deaths. Since we know the total mortality was 45 deaths for the entire trial, that would indicate mortality of approximately -9 patients in the Leron arm, that is to say, 9 Leron patients became immortal. In other words, almost 7 percent of the Leron arm attained immortality. The immortality p-value, however, does not reach statistical significance, so the FDA would not approve on this basis.
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