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Moderna's Phase 1 human trial revealed 100% of volunteers in the high-dose group suffered systemic side effects. Side effects included fatigue, chills, headache and myalgia (muscle pain); 21% suffered "one or more severe events."
A May 26, 2020, article7 in STAT news told the harrowing story of Ian Haydon, a healthy 29-year-old participant in Moderna's vaccine trial who suffered severe side effects requiring hospitalization.
While Haydon recovered from the side effects, which included a raging fever, fainting, nausea, muscle pain and generally feeling "as sick as he'd ever felt," just imagine what such side effects might do to an elderly person, an infant, young child or someone who is metabolically compromised or has an underlying condition such as a heart problem. For them, the reactions could be far worse and possibly fatal.
Disturbingly, in July 2020, it was reported8 that Moderna's 100-mcg dose vaccine — despite its 100% side effect ratio after the second dose — would proceed to Phase 3 trial assessment.
Like the Moderna vaccine, the AstraZeneca/Oxford University vaccine also appears to come with a shockingly high rate of side effects. Results9 from one of its Phase 1/2 studies published August 15, 2020, revealed a clear majority of participants experienced side effects, including fatigue, headache, muscle ache, malaise, chills and feeling feverish.
September 6, 2020, AstraZeneca paused its Phase 3 vaccine trial due to a "suspected serious and unexpected adverse reaction" in a British participant.10,11 The company did not divulge the nature of the adverse reaction.
However, The New York Times reported12 that "a person familiar with the situation, and who spoke on the condition of anonymity" said the individual" had been found to have transverse myelitis, an inflammatory syndrome that affects the spinal cord and is often sparked by viral infections."
September 12, 2020, the British Medicines Health Regulatory Authority gave AstraZeneca the go-ahead to resume its Phase 3 trial in the U.K., after an independent review found it "safe to do so."13,14
And here is yet another major surprise that hardly anyone knows. Offit warns there could be problems with Moderna's and BioNTech's messenger RNA (mRNA) vaccines because they have extraordinary shipping and handling needs that include using dry ice. "We've never done that before in this country," he told MarketWatch.15 "Never."