$PBIO It is estimated that more than 40% of all ne

$PBIO It is estimated that more than 40% of all new chemical compounds developed by the pharma industry are highly insoluble in water. To be effective as potential new drugs, most such molecules need to be processed into highly water-soluble solutions. The Company believes the UST platform can play a pivotal role in fulfilling this need. For example, PBI scientists evaluated the UST nanoemulsification platform on Prednisone, a widely prescribed corticosteroid with systemic anti-inflammatory and immunosuppressant properties. Prednisone is sparingly soluble in water and ethanol. When processed by the UST platform, Prednisone solutions became optically clear (signifying achievement of nanoemulsion status) and remained stable for many weeks at room temperature. Other nanoemulsions using this same formulation and UST processing have been shown by PBI scientists to remain stable at room temperature for six months and longer.