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From "up to date": Patients with severe disease

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Post# of 154844
(Total Views: 709)
Posted On: 10/04/2020 8:01:40 PM
Posted By: MD VIROLOGIST
Re: viridi #59699
From "up to date":

Patients with severe disease who are receiving supplemental oxygen – For patients on supplemental oxygen (including those who are on high-flow oxygen and noninvasive ventilation), we suggest low-dose dexamethasone. Trial data suggest that dexamethasone improves mortality in patients who are on noninvasive oxygen supplementation; it is uncertain if there are particular patients in this relatively heterogeneous group who would benefit more than others.

For patients who are on low-flow supplemental oxygen only, we also suggest remdesivir. Subgroup analysis of trial data suggests that remdesivir improves mortality in patients who are on low-flow supplemental oxygen, but clinical benefit is less certain in patients who need higher levels of noninvasive support (eg, high-flow oxygenation and noninvasive ventilation). We also suggest remdesivir in patients with higher levels of noninvasive support, but prioritize it for patients on low-flow supplemental oxygen.

Of course I am not sure if this applies to POTUS, unless I had the opportunity to see his chart.


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