I have been thinking about this all day and this i
Post# of 155120
(Total Views: 572)
Posted On: 10/03/2020 5:16:51 PM
Re: crazyjogger925 #59501
I have been thinking about this all day and this is just my opinion and speculation.
Yes, remdesivir has potential kidney/liver side effects and if they decided to give it to him aggressively, they would want him to be in a setting where he could receive the best critical care, if needed. Or if anything like clotting started to happen and cardiac stuff.
Trying to be as impartial as I can, I believe there is no reason to disbelieve what his doctor reported this morning.
On the other hand, if he were in bad shape (which doesn't seem likely only 72 hours into the disease) there is a case to be made that they would not report it to the public.
In the event that he is or does move into the severe category, it is my belief that they might give him an unapproved experimental drug in addition to dexamethasone. I think they would only do this if he took a turn for the worse and dexamethosone was not working. It is my belief that leronlimab would be one of four drugs they might consider. They might consider RLF100, leronlimab, lenzilumab, or the oncoimmune drug which just reported trial data.
I don't know of another drug they would consider, but I don't think they are going to even consider it unless the situation becomes dire.
However, I don't think it will become dire because he got the REGN early. (I don't think remdesivir does much, but I think the REGN might help decrease viral load to the point that he can fight it off.) Also he is being handled with kid gloves by an incredible team. So, I am thinking that he will recover without an experimental drug other than the REGN he's been given.
I am sorry I went on and on. I am just trying to figure this out....
Yes, remdesivir has potential kidney/liver side effects and if they decided to give it to him aggressively, they would want him to be in a setting where he could receive the best critical care, if needed. Or if anything like clotting started to happen and cardiac stuff.
Trying to be as impartial as I can, I believe there is no reason to disbelieve what his doctor reported this morning.
On the other hand, if he were in bad shape (which doesn't seem likely only 72 hours into the disease) there is a case to be made that they would not report it to the public.
In the event that he is or does move into the severe category, it is my belief that they might give him an unapproved experimental drug in addition to dexamethasone. I think they would only do this if he took a turn for the worse and dexamethosone was not working. It is my belief that leronlimab would be one of four drugs they might consider. They might consider RLF100, leronlimab, lenzilumab, or the oncoimmune drug which just reported trial data.
I don't know of another drug they would consider, but I don't think they are going to even consider it unless the situation becomes dire.
However, I don't think it will become dire because he got the REGN early. (I don't think remdesivir does much, but I think the REGN might help decrease viral load to the point that he can fight it off.) Also he is being handled with kid gloves by an incredible team. So, I am thinking that he will recover without an experimental drug other than the REGN he's been given.
I am sorry I went on and on. I am just trying to figure this out....
(0)
(0)