From a link previously posted: https://jamanetw

From a link previously posted:

https://jamanetwork.com/journals/jama/fullarticle/2771111

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“I joke, ‘Well, COVID has eaten my brain, because I can’t remember how to remember words, keep track of medication,’” she said. “ My brain just feels like there’s a fog. ”

Lockman considers herself to be a “long hauler,” someone who still hasn’t fully recovered from COVID-19 weeks or even months after symptoms first arose. She serves as an administrator of 2 “Long Haul COVID Fighters” Facebook groups, whose members now number more than 8000.

The longer the pandemic drags on, the more obvious it becomes that for some patients, COVID-19 is like the unwelcome houseguest who won’t pack up and leave.

“Anecdotally, there’s no question that there are a considerable number of individuals who have a postviral syndrome that really, in many respects, can incapacitate them for weeks and weeks following so-called recovery and clearing of the virus,” Anthony Fauci, MD, director of the National Institute of Allergy and Infectious Diseases, said in July during a COVID-19 webinar organized by the International AIDS Society.

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Lockman and many other long haulers describe their most debilitating persistent symptom as impaired memory and concentration, often with extreme fatigue.

The effects are different from the cognitive impairment patients might experience after a critical illness, according to Hope. When it comes to COVID-19, “I do think there’s a subset of patients [who] weren’t even in the hospital who have a postviral brain fog ,” he said.

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From another study in Korea (also posted here)

https://www.reuters.com/article/us-health-cor...SKBN26K1CA

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Fatigue was the most common side-effect with 26.2% reading, followed by difficulty in concentration which had 24.6% , Kwon said.

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Here is where we should come in. If the Long Hauler syndrome has a component of brain fog one likely needs something to go through the brain barrier. If it is a immune disfunction we could help as well.

As there aren't many drugs that can claim this imo it would be a good move to try LL in long haulers (alone or in combination with other drugs), however this should be attempted only if feasible without affecting other programs (I am thinking Oncology and HIV here).