Leronlimab for Variola? Hey Chowder! Variola ma
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Hey Chowder! Variola may also be in play for Leron as there is evidence it uses CCR5 to enter cells. Maybe Leron could be the second antiviral for the SNS.. would you happen to know of any other companies far along with an antiviral for Variola?
"The smallpox virus also has more biological similarities to HIV-1 than does bubonic plague, the authors point out. Plague is a bacterial disease, and there is no evidence that the bacterium, Yersinia pestis, uses the CCR5 receptor in infection. The bacteria actually reproduce outside immune cells.
Smallpox, on the other hand, is a virus based on RNA, just like HIV, she said. And there is some evidence that smallpox, Variola major, uses chemokine receptors like CCR5 to enter cells. "
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