I have always thought that the (anecdotal)evidence from the 60+/- eind patients, being so positive, should have given the DSMB cause to watch the CD-12 trial very closely. After all, the whole world knows the s/c patients are at risk of morality(around 20%+). So when an allegedly promising game changer sooner starts a trial and puts the FDA on notice, why not have the safety board jump on the mortality outcomes? Think about the fact that at 20% mortality in the placebo arm that would mean 13 dead patients (assuming 65 pts in placebo group vs 130 in LL group) at the interim "check point". And the best case scenario for LL could be ZERO dead. Excuse me, hello, any lawyers on the board? Doesn't that sound pretty neglectful on the FDA's part. I sure would be pissed if any of my family were in the placebo group that died, especially if they were anywhere after the first or second deaths while there were no deaths in the LL group. I'm sure there is someone on our board that knows some medical malpractice attorneys that could look into something like this...or not???
Ah yes, election season is upon us once more - that magical time when political pundits start frothing at the mouth, desperately trying to convince you their candidate won't totally nuke the economy. And of course, few sectors feel those ripple effects quite like the cut-throat real estate game.
As we careen toward the 2024 presidential showdown, potential homebuyers and sellers are sweating bullets over how the political tides could pummel their investments and dictate market dynamics. B... Continue Reading
Category: CryptoTotal Views: 100 By : EditorUpdated: 05-21-2024
Crypto. It's all anyone can blabber about these days - whether they actually know what they're rambling on about or not. Stories of overnight crypto millionaires and revolutionary new money tech are inescapable. No wonder the buzz around investing in this wild new asset class just won't quit. In this extensive tell-all, we're diving head first into the frothy crypto waters to answer the burning question: Is it actually worth taking the plunge?
What is Cryptocurrency?
At its... Continue Reading
Category: MarketsTotal Views: 98 By : EditorUpdated: 05-21-2024
Overview
The closing bell today was more of a whisper than a bang, but that hushed tone still managed to etch some fresh records into the financial almanacs. The S&P 500 and Nasdaq flew to new highs, while the Dow knocked on the door of its own peak. Let's break it all down - the plays, the numbers, and what it all means for your portfolio.
U.S. Market Scorecard
Index Rundown
S&P 500: Inched up 0.3% to 5,321.41 for a shiny new record. Small gains, but they all add up i... Continue Reading
Category: InvestingTotal Views: 244 By : EditorUpdated: 05-20-2024
Do you want to be free with money and safe in the future? Think about making money over time. This helps you and your loved ones. Stocks are called the way to meet these long-term goals. They give chances to grow, make income, and build money that lasts. The stock market seems hard at first. But with the right knowledge, stocks can be rewarding. They can bring you gains. So why should you try stocks? How can they lead to money success?
We will... Continue Reading
Category: StocksTotal Views: 246 By : EditorUpdated: 05-20-2024
Introduction: Real Facts About Penny Stocks
Do you feel confused about penny stocks? Is it hard to tell facts from fiction? Worried about risks? Wonder if penny stocks are worth it?
We look at common misunderstandings that may stop you from making good choices in the stock market.
What to expect
From learning penny stock basics to tips for reducing risks, this blog gives you knowledge to make informed choices about trading penny stocks.
Uncover hidden... Continue Reading
Category: Real EstateTotal Views: 299 By : EditorUpdated: 05-20-2024
Mortgage pre-approval is very important in a scenario where you need it to be like a serious buyer and, it is the best weapon in this case. It is not only your way to the home but also your ticket above the queue of other potential buyers who are interested in the same property.
What is Mortgage Pre-Approval?
Pre-approval means a lender has looked at your money situation. They checked your credit score, income, and debt. Then they approved you for a certain loan am... Continue Reading
Category: MarketsTotal Views: 307 By : EditorUpdated: 05-20-2024
The week of 20th May, 2024 finds the global markets presenting a mixed picture for investors: There is rife opportunity, but also risk. Let us break down what investors need to be looking out s is know about in order to assess the situation.
Market Performance In Review
European Stocks
The Stoxx 600 index fell by 0.24%. Noteworthy was the fact that performance of sectors totally varied: energy stocks under-performed mining shares took lead on this occasion. This may suggest an industry-... Continue Reading
Category: EconomyTotal Views: 309 By : EditorUpdated: 05-20-2024
Introduction
Mortgage rates are like fashion metal gear wrapped around the relationship between the sector of economies and the psyche of a the common man, live, and dynamic. They are seen as effective barometers of the economic health and consumer sentiment. The efficiency and effectiveness of evaluating the mortgage rate environment of current times can solely be achieved through a comparison with earlier years so that one can develop an understanding of the housing market features and the ... Continue Reading
Category: EconomyTotal Views: 385 By : EditorUpdated: 05-19-2024
Introduction: Inflation and Deflation
In the economic realm, inflation and deflation are fundamental in the field of economics. Mastering these topics requires both sellers, buyers, and policymakers to have an insightful understanding as well.
What is Inflation?
Inflation alludes to a gradual, long life increase in the prices of services along with the goods in an economy. Gradually, it leaves people with purchasing power as money value buildings up where the price for the same amount o... Continue Reading
Introduction to Setting SMART Financial Goals
When it comes to financial success and secure a lavish future, setting SMART financial goals is one of the easy ways. It doesn't matter whether you wish to get married or save for a down payment for your house; one thing cleared is that having a clear and strategic approach to goals is essential.
Setting SMART goals mean that your ambitions meet the Specific, Measurable, Achievable, Relevant, and Timely criteria. With such a structure, purp... Continue Reading