27% mortality in the placebo arm would be around 1

27% mortality in the placebo arm would be around 16 or 17.

That would probably get the p value done at 0.05 if the wolframalpha two binomial distribution test is the correct statistical math for CD12.

Problem is that the 27% number was measured between Feb and April.

The mortality is lower now, maybe by half.

13% of 65 is only 7 or 8. That makes for a very difficult challenge to get p value below 0.05 on the two binomial distribution test.

but maybe the two binomial distribution test is not the correct statistical math for this CD12 trial.