I was doing some deep thinking about convalescent
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Posted On: 08/24/2020 11:48:39 AM
I was doing some deep thinking about convalescent blood plasma last night. If the COVID-19 strain from the infected patient generated specific antibodies, would the patient have also possibly generated a spectrum of antibodies that are due to the "cytokine storm" ? Wouldn't those antibodies also include RANTES?
I don't believe the process they use to separate the platelets from plasma discern between immune cell types. Is anyone aware if they treat the plasma before it is administered to the recipient? Do they test the plasma for RANTES? Wouldn't the recipient then be potentially elevating their RANTES through the treatement? Would that elevated RANTES cause issues?
Would it not make sense to collect the blood plasma from patients who have been treated with Leronlimab? Their immune system will have been modulated to react and kill the coronavirus with more anti-inflammatory immune cells that are "pumped" up.
I wonder if Dr. BP has considered this? Anybody have him on speed dial?
I don't believe the process they use to separate the platelets from plasma discern between immune cell types. Is anyone aware if they treat the plasma before it is administered to the recipient? Do they test the plasma for RANTES? Wouldn't the recipient then be potentially elevating their RANTES through the treatement? Would that elevated RANTES cause issues?
Would it not make sense to collect the blood plasma from patients who have been treated with Leronlimab? Their immune system will have been modulated to react and kill the coronavirus with more anti-inflammatory immune cells that are "pumped" up.
I wonder if Dr. BP has considered this? Anybody have him on speed dial?
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