$PBIO has entered into a worldwide co-marketing ag
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Leica Microsystems ("Leica" is a leading global designer and producer of innovative high-tech precision optical systems for the analysis of microstructures. It is one of the market leaders in microscopy, pathology, diagnostics, and surgical microscopes. Users of Leica's instruments and services can be found in both clinical applications and broader life science research, several surgical specialties, disciplines associated with material sciences, the manufacturing industry, forensics services, and in classrooms around the world. Leica is a Danaher company.
PBI and Leica will co-market a novel, enabling technology platform that combines the Leica Laser Microdissection (LMD) System for precise excision of specific, minute sections of biopsy tissue with PBI's Pressure Cycling Technology ("PCT"-based Barocycler System for rapid protein extraction and digestion for sample preparation prior to mass spectrometry analysis. Specifically, both companies will promote an integrated biomarker discovery workflow designed to quickly and efficiently collect tissue sections excised by the Leica LMD and then drop the samples into PBI's consumable MicroTubes for rapid PCT processing. Proteins are then analyzed by mass spectrometry (MS), the global method-of-choice for high throughput and comprehensive protein analysis.
The integrated workflow of LMD and PCT was developed by Dr. Thomas P. Conrads, a nationally acclaimed protein chemist. Dr. Conrads is the Senior Director of Women's Health Research in the Inova Women's Service Line; he is also Chief Scientific Officer of the Women's Health Integrated Research Center (WHIRC) at Inova Health System.
Dr. Conrads said: "We believe that integrating LMD, PCT, and MS will improve our understanding of the complex tissue microenvironment and better enable identification of new biomarkers. We believe that the insights gained from applying this novel workflow will result in significant improvements in the clinical management of gynecologic and other cancers."
The global cancer biomarker market is expected to reach $136.5 billion by 2023.