You forgot MS too....
Post# of 154836
(Total Views: 843)
Posted On: 06/16/2020 6:46:33 AM
Re: Goosebumps #37879
You forgot MS too....<<Understanding what causes MS will speed the process of finding more effective ways to treat it and — ultimately — cure it, or even prevent it from occurring in the first place.
Immunologic Factors
In MS, an abnormal immune response causes inflammation and damage in the CNS(central nervous system). Many different cells are involved in the abnormal immune response. Two important types of immune cells are T cells and B cells.
T cells become activated in the lymph system and in MS, enter the CNS through blood vessels. Once in the CNS, T cells release chemicals that cause inflammation and damage. This results in damage to myelin, nerve fibers and the cells that make myelin. T cells are also important to help activate B cells and call on other immune system cells to participate in the immune attack.
T regulatory cells, a type of T cell, dampen or turn off inflammation. In MS, T regulatory cells do not function correctly and do not effectively turn off inflammation.
Cytotoxic or “killer” T cells directly attack and destroy cells bearing certain characteristics
B cells become activated with the help of T cells. B cells produce antibodies and stimulate other proteins and in MS, these cause damage in the CNS (this reads like a cytokine storm).
Researchers continue to search for other cells and processes that could be involved in MS. Ongoing efforts to learn more about the immune-mediated process in MS — what sets it in motion, and how to slow or stop it — will bring us closer to understanding the cause of MS, better therapies and ultimately a cure.
Immunologic Factors
In MS, an abnormal immune response causes inflammation and damage in the CNS(central nervous system). Many different cells are involved in the abnormal immune response. Two important types of immune cells are T cells and B cells.
T cells become activated in the lymph system and in MS, enter the CNS through blood vessels. Once in the CNS, T cells release chemicals that cause inflammation and damage. This results in damage to myelin, nerve fibers and the cells that make myelin. T cells are also important to help activate B cells and call on other immune system cells to participate in the immune attack.
T regulatory cells, a type of T cell, dampen or turn off inflammation. In MS, T regulatory cells do not function correctly and do not effectively turn off inflammation.
Cytotoxic or “killer” T cells directly attack and destroy cells bearing certain characteristics
B cells become activated with the help of T cells. B cells produce antibodies and stimulate other proteins and in MS, these cause damage in the CNS (this reads like a cytokine storm).
Researchers continue to search for other cells and processes that could be involved in MS. Ongoing efforts to learn more about the immune-mediated process in MS — what sets it in motion, and how to slow or stop it — will bring us closer to understanding the cause of MS, better therapies and ultimately a cure.
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