two sample test: 13/17 and 30/31 Sucess Thanks

two sample test: 13/17 and 30/31 Sucess

Thanks for the tutorial, Rex.

If 13 out of 17 placebo patients survive then only one death is permitted in the leronlimab arm.

The small sample size is risky.

Is there a similar simulator that can handle the parameterized portion of the trial? Each patient is evaluated as to several secondary endpoints, either as a binary result or a scalar result. Do you know of a simulator, like the Wolphram two sample binomial simulator, that could be used for the parameterized part of the trial?

And I guess wonder if binary results on the five secondary endpoints can be aggregated some how by combining the binary result of all five secondary endpoints even in the situation that a single endpoint does not have binary transitions for most of the patients.