Investors Hangout Stock Message Boards Logo
  • Mailbox
  • Favorites
  • Boards
    • The Hangout
    • NASDAQ
    • NYSE
    • OTC Markets
    • All Boards
  • Whats Hot!
    • Recent Activity
    • Most Viewed Boards
    • Most Viewed Posts
    • Most Posted
    • Most Followed
    • Top Boards
    • Newest Boards
    • Newest Members
  • Blog
    • Recent Blog Posts
    • Recently Updated
    • News
    • Stocks
    • Crypto
    • Investing
    • Business
    • Markets
    • Economy
    • Real Estate
    • Personal Finance
  • Market Movers
  • Interactive Charts
  • Login - Join Now FREE!
  1. Home ›
  2. Stock Message Boards ›
  3. Stock Boards ›
  4. CytoDyn Inc (CYDY) Message Board

JAK Inhibitors for Rheumatoid Arthritis WHAT IS

Message Board Public Reply | Private Reply | Keep | Replies (0)                   Post New Msg
Edit Msg () | Previous | Next


Post# of 154997
(Total Views: 711)
Posted On: 06/02/2020 8:28:14 AM
Avatar
Posted By: Rubraquercus
JAK Inhibitors for Rheumatoid Arthritis

WHAT IS A JAK INHIBITOR?

If you have rheumatoid arthritis (RA), your doctor may suggest Janus kinase (JAK) inhibitors to help ease your joint pain and swelling. These drugs tamp down your overactive immune system -- the body's defense against germs -- to help prevent damage to your joints.


JAK inhibitors belong to a family of medicine called DMARDs (disease-modifying antirheumatic drugs). Three JAK inhibitors, baricitinib (Olumiant),tofacitinib (Xeljanz), and upadacitinib (Rinvoq), are approved by the FDA to treat rheumatoid arthritis. More should appear in the next few years if they succeed in clinical trials.

How JAK Inhibitors Work
If you have RA, your body makes too many proteins called cytokines, which play a role in inflammation. Some cytokines attach to receptors on immune cells, like a key fitting into a lock. When that happens, messages are sent to the cell to make even more cytokines.

JAK inhibitors put a wrench in the process by blocking the messaging pathway. This calms down your immune system and helps ease your RA symptoms.

Who Benefits?
You may be among the many people with RA whose symptoms are well-controlled with an older drug, such as adalimumab (Humira) or methotrexate (Trexall). In that case, you may not need a JAK inhibitor.

But the older drugs don't always work for everyone. About 65% of people who take DMARDs, for example, get relief from symptoms. If you're not in this group, a JAK inhibitor might make a difference. In one study, about half of people with RA who didn't improve with biologic drugs had symptoms that were less severe after they took the JAK inhibitor tofacitinib for 3 months.


Another advantage of JAK inhibitors is that you can take them by mouth. You must inject biologics, such as adalimumab, into your skin, while doctors infuse others into the bloodstream. But you can take JAK inhibitors as a pill.



(0)
(0)




CytoDyn Inc (CYDY) Stock Research Links


  1.  
  2.  


  3.  
  4.  
  5.  






Investors Hangout

Home

Mailbox

Message Boards

Favorites

Whats Hot

Blog

Settings

Privacy Policy

Terms and Conditions

Disclaimer

Contact Us

Whats Hot

Recent Activity

Most Viewed Boards

Most Viewed Posts

Most Posted Boards

Most Followed

Top Boards

Newest Boards

Newest Members

Investors Hangout Message Boards

Welcome To Investors Hangout

Stock Message Boards

American Stock Exchange (AMEX)

NASDAQ Stock Exchange (NASDAQ)

New York Stock Exchange (NYSE)

Penny Stocks - (OTC)

User Boards

The Hangout

Private

Global Markets

Australian Securities Exchange (ASX)

Euronext Amsterdam (AMS)

Euronext Brussels (BRU)

Euronext Lisbon (LIS)

Euronext Paris (PAR)

Foreign Exchange (FOREX)

Hong Kong Stock Exchange (HKEX)

London Stock Exchange (LSE)

Milan Stock Exchange (MLSE)

New Zealand Exchange (NZX)

Singapore Stock Exchange (SGX)

Toronto Stock Exchange (TSX)

Contact Investors Hangout

Email Us

Follow Investors Hangout

Twitter

YouTube

Facebook

Market Data powered by QuoteMedia. Copyright © 2025. Data delayed 15 minutes unless otherwise indicated (view delay times for all exchanges).
Analyst Ratings & Earnings by Zacks. RT=Real-Time, EOD=End of Day, PD=Previous Day. Terms of Use.

© 2025 Copyright Investors Hangout, LLC All Rights Reserved.

Privacy Policy |Do Not Sell My Information | Terms & Conditions | Disclaimer | Help | Contact Us