This has been answered like 3-4 times. Watch the video. Generate your own understanding. You seem hyper concerned with the trial results and it's obvious you have no understanding of the MOAs and their impact on clinical outcomes. Based on the responses it's obvious you haven't read and comprehended the pre print. Not trying to be mean but nobody can hold your hand on this. You say you've done your own "D" yet you haven't even watched the video and given yourself a chance to generate your own answers. How you could not the understand the structure of how the trial is ran is beyond me.