There are, which would make a vaccine more difficult IMO. I envision this more like the flu where vaccines provide partial but not full immunity but have to be updated annually due to mutation. Not sure how feasible and cost effective this would be, but flu shots are regularly updated so maybe be it is possible. I believe the virus itself is larger and more complicated than the flu which may make this difficult, but I do not know for sure.
I was merely commenting to my perception of Fauci. When he talks, I get the sense of someone washed up saying, "Hey see I am relevant again since the mid eighties. I got my second fifteen minutes". I think that is the extent of his regular referral back to HIV, rather than he is actively thinking about leronlimab. I hope this changes soon and I am wrong here.