Not sure if this has been posted about remdesivir:
Post# of 148185
https://threadreaderapp.com/thread/1256242036015063042.html
"Where do the Shenanigans come in? Well, remember how maybe this Chinese trial showed a shortened course in a subset of patients? Like tamiflu? But didn’t change mortality?
Well a month ago the NIAID trial changed their endpoints to remove death and instead look at dz duration.
No really. They changed the destination half way through the race to match the only positive outcome of another trial, that they (or Gilead at least) certainly had a copy of the paper once it was submitted to Lancet."
Gaming the system!