I think we will be having a bla conversation of some sort for the next few years, every one of our 5 to ?*?*? Indications will require a separate one, and I would say that none will be more anticipated than this first one but I'm not so sure that will be true especially when it comes to cancer. I picture us sitting at 40 a share saying "come on you have been pushing this solid tumor bla back for months now just like you did HIV, luckily the FDA filed the covid19 for us, come on let's get it filed already!"