Not trying to burst anyones bubble with trying to

Not trying to burst anyones bubble with trying to predict manufacturing capacity, but without knowing some key information it is pointless...but I get some people are bored.

When estimating production output you need to know a few things (none of which we know):

what is the final volume of the production bioreactor?

What is the g/L yield of the production bioreactor?

Is the production bioreactor a fed-batch process or perfusion process?

Note, first generation (pre-market) processes like ours are notoriously inefficient, especially for cash-strapped companies that can't afford development for a second generation process (I'm not sure if Cytodyn has done this or not)

When a bioreactor "size" is given it is hardly ever the working volume and most likely the max capacity of that tank. Production bioreactor output is measured in grams per liter. For fed batch processes this ranges from 0.1 - 7 g (big range) and the upper end of that range is unlikely IMO.

The overwhelming majority of each liter is cell matter, other proteins, nutrients, and cell waste. IF this is a perfusion process in the production bioreactor output could be higher but the calculation is even more complex and adds more unknown variables. I would guess its a fed-batch process.

yes a range can be established by doing some calculations and a lot of guess work, but I don't know how such a large range will be of any value.

If you're that interested, I would try asking Nitya Ray our CTO to provide the average yield per production bioreactor run i.e how much do we get out a single run. the answer should come back in kilograms. Then you will need to know the average yield % after purification operations (I'm not even sure he'd tell you).

I would ask, but I think our executives have it covered, and their time is better spent elsewhere.