Yes. We need to remember that ultimate objective
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Posted On: 04/02/2020 8:39:22 AM
Yes. We need to remember that ultimate objective is to help the patients survive:
If the improvement in cytokines, IL-6, and a trend toward the normalization of the CD4/CD8 ratio results in improved survival rates we are contributing (and will be approved as a result).
When the time comes, the real question is: how are the patients doing so far?. Out of ventilators mean they very likely made it, still in ventilators and improving that they will likely make it. Not improving after few days that we could not help them and the odds are negative.
From CDY press release:
So, re-stating the question: will the significant improvement in several important immunologic bio-markers announced today result in 8 patients surviving (not clear about the other 2)?? This is only 3 days data so nobody knows that answer yet. For what we know most of them are still in ventilators hopefully improving:
A PR from Nader will give us lots of "color" regarding what is happening ( maybe more than one are out of respirators already) but, with trials on going as we speak he might be a bit reluctant to provide details before outcomes are achieved.
Quote:
Patients enrolled in this trial are expected to be administered leronlimab for two weeks with the primary endpoint being the mortality rate at 14 days.
If the improvement in cytokines, IL-6, and a trend toward the normalization of the CD4/CD8 ratio results in improved survival rates we are contributing (and will be approved as a result).
When the time comes, the real question is: how are the patients doing so far?. Out of ventilators mean they very likely made it, still in ventilators and improving that they will likely make it. Not improving after few days that we could not help them and the odds are negative.
From CDY press release:
Quote:
Recent data from China indicates mortality rate among COVID-19 patients requiring mechanical ventilator is more than 85%
So, re-stating the question: will the significant improvement in several important immunologic bio-markers announced today result in 8 patients surviving (not clear about the other 2)?? This is only 3 days data so nobody knows that answer yet. For what we know most of them are still in ventilators hopefully improving:
Quote:
The current data suggests a trend toward the restoration of immune function and mitigation of the cytokine storm.
A PR from Nader will give us lots of "color" regarding what is happening ( maybe more than one are out of respirators already) but, with trials on going as we speak he might be a bit reluctant to provide details before outcomes are achieved.
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