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  4. Generex Biotechnology Corp. (GNBTQ) Message Board

Moderna is not, repeat is not, ahead of GNBT on th

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Post# of 36567
(Total Views: 260)
Posted On: 02/28/2020 1:04:53 PM
Posted By: Creekrat
Moderna is not, repeat is not, ahead of GNBT on the vaccine front. They don't even know if it works - it is a new type - RNA based vaccine. They are just now starting phase 1 safety trials. CDC says it would take 12-18 months to field the vaccine, if it even works.

Here is a write up on them:

Quote:
Moderna began developing its coronavirus vaccine with the NIH in January with the help of funding from the Coalition for Epidemic Preparedness Innovation (CEPI). NIAID will conduct a clinical trial of the vaccine at Kaiser Permanente Washington Health Research Institute in Seattle. The study is designed to test the safety of the vaccine in 45 healthy adults.

The trial could begin in March or April, and investigators should be able to tell if the vaccine is safe and immunogenic after three months. If the Phase I trial is successful, a larger trial of hundreds to thousands of people will be launched to see if the vaccine is effective, NIAID director Anthony Fauci said in a White House press conference. That trial would take an additional 6 to 8 months.

“So although this is the fastest we’ve ever gone from a sequence of a virus to a trial,” Fauci said, wide deployment of a vaccine will still take 12 to 18 months, at best.

Perhaps the biggest risk with Moderna’s approach is that little is known about how well mRNA vaccines work in humans compared to traditional vaccines. Moderna has tested six other mRNA vaccines in Phase I trials for infectious diseases including influenza, chikungunya, respiratory syncytial virus, and Zika, but they are all years away from approval.

Manufacturing could also pose a problem. Although mRNA vaccines can be made faster than egg- and cell-based vaccines, Moderna has not indicated whether it has the capacity to scale up production for the millions of doses that could eventually be needed in the US. The company did not respond to an interview request.



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