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Entyvio side effects
Entyvio can cause mild or serious side effects. The following list contains some of the key side effects that may occur while taking Entyvio. This list does not include all possible side effects.
For more information on the possible side effects of Entyvio, or tips on how to deal with a troubling side effect, talk with your doctor or pharmacist.
More common side effects
The more common side effects of Entyvio include:
runny nose
sore throat
respiratory infection such as bronchitis or sinus infection
headache
joint pain
nausea
fever
fatigue
cough
flu
back pain
rash or itchy skin
Serious side effects
Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following:
Allergic reactions. Some people can have allergic reactions when Entyvio is given. These are usually not severe, but may be severe in some cases. Administration of Entyvio will need to be stopped if a severe reaction occurs. Symptoms of an allergic reaction may include:
trouble breathing
itchy skin
flushing
rash
Liver damage. Some people who receive Entyvio can experience liver damage. If you develop liver damage symptoms, your doctor may stop your treatment with Entyvio. Symptoms of liver damage can include:
yellowing of your skin or the whites of your eyes
fatigue
stomach pain
Cancer. During studies of Entyvio, about 0.4 percent of those who received Entyvio developed cancer compared to about 0.3 percent who received a placebo. Whether Entyvio increases the risk of cancer isn’t clear.
Infections. People who take Entyvio have an increased risk of infection, such as the common cold or flu. More serious infections may also occur. These might include tuberculosis or an infection in the brain called progressive multifocal leukoencephalopathy (see below). If you develop a severe infection while taking Entyvio, you may need to stop taking the medication until the infection has been treated.
PML
Progressive multifocal leukoencephalopathy (PML) is a serious viral infection of the brain. It typically only happens in people whose immune system isn’t fully functioning.
During studies, PML did not occur in anyone who took Entyvio. However, it has occurred in people receiving medications that are similar to Entyvio, such as Tysabri (natalizumab).
While you take Entyvio, your doctor will monitor you for symptoms of PML. These symptoms may include:
weakness on one side of your body
vision problems
clumsiness
memory problems
confusion
Hair loss
Hair loss isn’t a side effect that has occurred in studies of Entyvio. However, some people have had hair loss while taking Entyvio. It’s not clear if Entyvio is the cause of hair loss.
Weight gain
Weight gain isn’t a side effect that has occurred in studies of Entyvio. However, some people who take Entyvio say that they gain weight. Gaining weight may be the result of healing in the gut, especially for those who’ve lost weight due to a flare-up of symptoms of the condition being treated.
Skin side effects
Rash and itchy skin can occur in some people who take Entyvio. In studies, rash or itchy skin happened in about 3 percent of those receiving Entyvio.
Joint pain
In studies, about 12 percent of people who received Entyvio experienced joint pain.
Headache
In studies, about 12 percent of people who received Entyvio experienced headaches.
Depression
Depression isn’t a side effect that has occurred in studies of Entyvio. However, some people have had depression while taking Entyvio. It’s not clear if Entyvio was the cause of their depression.
Fatigue
In studies, about 6 percent of people who received Entyvio experienced fatigue.
Muscle pain
In studies, about 3 percent of people who received Entyvio had pain in the muscles of their arms and legs.
Diarrhea
Diarrhea isn’t a side effect that has occurred in studies of Entyvio. However, some people have had diarrhea while taking Entyvio. It’s not clear if Entyvio is the cause of diarrhea.
Severe diarrhea could be a symptom of an infection. If you have severe diarrhea while receiving Entyvio, call your doctor.