For me it really depends on what is happening with the science and progress. For example it might be easy to say Is sell x number of shares at say $5. But it depends on when we hit $5. If it happens before revenue, it stands to reason there is still upside left. And I would be inclined to hold.
If however we have our BLA approved and are selling Lero and seem to have peaked I would be more inclined to sell.