Patent protection in U.S. until 2037. NEW YORK, J
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NEW YORK, Jan. 08, 2020 (GLOBE NEWSWIRE) -- Anavex Life Sciences Corp. (“Anavex” or the “Company”) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company developing differentiated therapeutics for the treatment of neurodegenerative and neurodevelopmental disorders including Alzheimer’s disease, Parkinson’s disease, Rett syndrome and other central nervous system (CNS) disorders, today announced that the United States Patent and Trademark Office (USPTO) granted U.S. Patent No. 10,507,196 to support Anavex’s leading drug candidate, ANAVEX®2-73 (blarcamesine) for the treatment of neurodevelopmental disorders including Rett syndrome, and multiple sclerosis.
Anavex’s newest patent is expected to remain in force at least until 2037, not including any patent term extensions. It covers methods of treatment for neurodevelopmental disorders including Rett syndrome, autism spectrum disorder, Angelman syndrome, and cerebral palsy, among others, and also treatment for multiple sclerosis, using ANAVEX®2-73 (blarcamesine). ANAVEX®2-73 (blarcamesine) is currently in several clinical studies for Rett syndrome, including the U.S. Phase 2 Rett syndrome study1 and the AVATAR Rett syndrome study2, with the international EXCELLENCE Rett syndrome study of ANAVEX®2-73 (blarcamesine) in pediatric patients scheduled to initiate early 2020. The ‘196 patent adds important coverage for ANAVEX®2-73 (blarcamesine) treatments for Rett syndrome and multiple sclerosis.
“We are extremely pleased with the continued development of the patent portfolio for ANAVEX®2-73 (blarcamesine). This new issuance of the U.S. patent continues to expand the breadth and depth of our intellectual property and is another step in the development of a robust patent portfolio relating to ANAVEX®2-73 (blarcamesine),” said Christopher U. Missling, PhD, President and Chief Executive Officer of Anavex.
ANAVEX®2-73 (blarcamesine) is an orally available, small-molecule activator of the sigma-1 receptor which, data suggest, is pivotal to restoring neural cell homeostasis and promoting neuroplasticity.3