Yes , many realizing now that PrEP is very importa

Yes , many realizing now that PrEP is very important ,at least until we have a cure and vaccine for HIV ...

So BP advertise very much their products.
Until now Truvada was it ...

So lets review the problems with it..

Truvada...
It is 2 HAART medicine in one ...

Emitricitabine and Tenofovir Discoproxil Fumarate...

And a problem with it...

--On its own cant suppress HIV , so some patients developed HIV taking that as a PrEP.
--and some patient can develop resistant HIV taking that for PrEP.
--do not cover resistant HIV.

Common side effects.

--Headache,
--Abdominal pain
--weigh loss

Serious side effects :

--Worsening of Hepatitis B infection.
--Kidney problems , including kidney failure,
--Lactic acidosis , rarely but sometimes can lead to death.
--Severe liver problem,
--Bone problem,
--cant take during pregnancy or breast feeding , may harm baby,
--May interact with many other drugs for many different reasons ..including some drugs given for Hepatitis B and C.

Because of all this , and IMO business decision , now Gilead came up with Descovy for PrEP,

It is like Truvada but with lower dose of Tenofovir , so company feel that side effects should be little lower..

If Dr Sacha will prove that once a month SC injection is working for PrEP with Leronlimab , we be a big winners....



IMO as always.