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The study, A Safety and Efficacy HemoStyp Hydrocolloid Test, was done by creating bilateral femoral arteriovenous fistulas in swine. HemoStyp thrombin hydrocolloid was applied to the anastomosis suture line on one side for the cessation of bleeding, while the market leading competitive product was applied to the anastomosis suture line on the opposite side for the cessation of bleeding. Time to cessation:
Animal 1: HemoStyp Hydrocolloid Product 35 Seconds; Competitive Product 1 Min 25 Seconds
Animal 2: HemoStyp Hydrocolloid Product 35 Seconds; Competitive Product 1 Min 55 Seconds
Animal 3: HemoStyp Hydrocolloid Product 25 Seconds; Competitive Product 2 Min 20 Seconds
After the completed hemostatic test, an autopsy with pathologic evaluation was performed three weeks following the procedures and showed no difference in scarring and inflammation between the two hemostatic agents. Pathology was completed by Thomas J. Baldwin, DVM, PhD, DACVP Director, Utah Veterinary Diagnostic Laboratory, an affiliate of Utah State University, on November 22, 2019.