Obviously, and most importantly, great news today

Obviously, and most importantly, great news today for that first patient! Let's hope the results are sustained and that reduced CTC, etc. translate into increased OS as predicted.

On science, to me the unanswered question is whether, on a long enough timeline, cancer finds a "work-around" to the CCL5-CCR5 signalling pathway. Research seems to be a bit muddy on that point, but enough human data and we should know the answer.

Generally, I am still long here, have not sold a share, and do not plan to. Like many shareholders, however, I am frustrated by the continued inability to translate good science into SP appreciation.

We all know WHY the SP has not appreciated as expected over the past 3 years, despite the steady drumbeat of good news (OTC/warrant raises/noteholders).

I am waiting to see WHAT management can/will do to break this cycle that, it should be noted, management created by virtue of its decisions over the past 3-5 years.

If nothing breaks soon, I expect a 14a requesting an increase in the total authorized shares, and I don't think any of us want to see what happens to the SP after that request.