But in this concrete situation, how will a sudden

But in this concrete situation, how will a sudden leadership change help? If NP were to be replaced with that slick Matinas guy you like on Monday, would the partnership deal magically close on Tuesday and BLA submitted on Tuesday? Don't think so... Or would he merely amaze anyone with his ProActive interview performance? You have lobbied for replacing him for quite some time and it is your privilege to continue doing so but no majority for this is (currently) at sight.