AVXL granted patent: Anavex Life Sciences Corp.

AVXL granted patent:

Anavex Life Sciences Corp. (“Anavex” or the “Company”) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company developing differentiated therapeutics for the treatment of neurodegenerative and neurodevelopmental disorders including Alzheimer’s disease, Parkinson’s disease, Rett syndrome and other central nervous system (CNS) disorders, today announced that the United States Patent and Trademark Office (USPTO) granted U.S. Patent No. 10,426,754 to support Anavex’s leading drug candidate, ANAVEX®2-73 (blarcamesine) for the treatment of Alzheimer’s disease.

Anavex’s newest patent is expected to remain in force at least until 2037, not including any patent term extensions. It covers compositions of matter directed to crystalline ANAVEX®2-73 (blarcamesine), and methods of treating Alzheimer’s disease using crystalline ANAVEX®2-73 (blarcamesine). ANAVEX®2-73 (blarcamesine) recently completed a successful Phase 2a clinical trial for Alzheimer’s disease and is currently in clinical studies in a larger Phase 2b/3 study for Alzheimer’s disease, among other studies (NCT03790709). The ‘754 patent adds important coverage for crystalline ANAVEX®2-73 (blarcamesine) dosage forms for treating Alzheimer’s disease.

“We are extremely pleased with the continued development of the patent portfolio for ANAVEX®2-73 (blarcamesine). This new issuance of the U.S. patent continues to expand the breadth and depth of our intellectual property and is another step in the development of a robust patent portfolio relating to ANAVEX®2-73 (blarcamesine),” said Christopher U. Missling, PhD, President and Chief Executive Officer of Anavex.

ANAVEX®2-73 (blarcamesine) is an orally available, small-molecule activator of the sigma-1 receptor which, data suggest, is pivotal to restoring neural cell homeostasis and promoting neuroplasticity.1

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