Genome Editing Genome Engineering Market Key Vendors, Growth
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Genome Editing/Genome Engineering Market : prominent players
Companies are involved in development of the products by the virtue of strategic partnerships. Many companies are taking benefit of developments in DNA engineering technology to develop products for the non-medical purposes.Recently in 2018, Merck, a renowned science and tech company, announced a partnership with China based stem cell research university, Tongji to further expand the field of genome editing.
The players are involved in either in-house research or acquisition of other businesses or cross licensing agreements. The agreements enable the licensing of intellectual property based on novel proteins that may not be affected by arguments in order to continue development.
Some of the prominent players operating in this vertical include Caribou Biosciences, Inc., Editas Medicine, Sangamo, Recombinetics, Inc, CRISPR THERAPEUTICS, Thermo Fisher Scientific, Inc., Intellia Therapeutics, Inc., and The Sigma Aldrich Corporation.
Genome editing also commonly known as genome engineering is a certain type of genetic engineering wherein the DNA in the genetic material of a living organism is altered by deleting, inserting, replacing, modifying or replacing the DNA. Since the 1970s, the method of introducing new genetic elements into organisms had already existed.
However, it was observed that this technology where the DNA was inserted into the host’s genome was random in nature and could result in the impairment of the other genes in the organism. This began the active search for alternative methods which targeted the inserted genes only in specific sites within an organism genome. Not only would they be targeting only specific sites, but these technologies would also, reduce off-target effects which now allowed for the editing of specific sequences within a genome.
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Strong product pipeline to boost the market
Strong product pipeline are anticipated to impact the industrial growth over the forecast period of 2019–2030. The novel products are designed to help in development of DNA targeting, with improved flexibility, specificity of nuclease, and the ease of Adeno-Associate Virus (AAV) packaging for delivery. Moreover, utilization of the technique through a number of methods such as disruption of viral DNA, correction in the toxic mutations, or the addition of therapeutic transgenes is projected to boost the adoption.
Increasing application of the technology to propel the market growth
Application of the technology for cell line genetic editing or engineering in the form of gene therapy and stem cell therapy accounted for the considerable share and is estimated to register lucrative growth. Furthermore, use of the genome editing technology for the development of novel molecules which can be targeted for treating various diseases such as infectious diseases and hematological malignancies is likely to drive the adoption of the technology in the coming years.
Safety concerns to remain the major restraining factors
Toxicity owing to off-target effects of the nucleases is a major safety concern for the market restraining the market growth. In addition, the IP disputes relating to CRISPR technology between the industry players is estimated to restrain growth in near future.
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Table Of Contents:
1. COMPETETIVE LANDSCAPE
1.1. Market Share Analysis (2018)
1.2. Key Strategies Assessment
1.2.1. New Product Launches
1.2.2. Merger & Acquisitions
1.2.3. Agreements, Collaborations, & Partnerships
1.2.4. Expansions
1.2.5. Other Strategies
2. COMPANY PROFILES (Business Overview, Products/Services Offered, Financial Performance, R&D Intensity, Marketing & Sales Intensity, Recent Developments, Analyst Corner)*
2.1. Merck Group
2.2. Horizon Discovery Group
2.3. Genescript
2.4. Thermo Fisher Scientific
2.5. Lonza
2.6. Origene Technologies
2.7. New England Biolabs
2.8. Sangamo Bioscience
2.9. Editas Medicine, Inc.
2.10. CRISPR Therapeutics AG
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