I don't know that they would adjust the Carboplati
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Posted On: 06/14/2019 11:04:57 AM
I don't know that they would adjust the Carboplatin dose for this trial? Per the clinical trial website, they are using AUC 5 Carboplatin for this PIb/II trial.
https://clinicaltrials.gov/ct2/show/NCT03838367
Quick research, I found that AUC 5 Carboplatin dose level is a specific calculation based on sex, age, weight and serum creatinine with maximum dose levels determined by AUC level.
https://www.nccn.org/professionals/OrderTempl...ndix_B.pdf
https://clinicaltrials.gov/ct2/show/NCT03838367
Quick research, I found that AUC 5 Carboplatin dose level is a specific calculation based on sex, age, weight and serum creatinine with maximum dose levels determined by AUC level.
https://www.nccn.org/professionals/OrderTempl...ndix_B.pdf
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