Just a rough estimate based on the chart that was
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Posted On: 05/06/2019 8:41:45 AM
Just a rough estimate based on the chart that was posted in 2010 when they listed the half-life
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856743/
It is log scale so hard to estimate, 162mg peak was 6.1 mg/L , So I made lines for 3 and 1.5, look like 4.5 day half-life at that dose. Then 324mg was 13.8 peak, so that is looking like 6.5 day.
So the 10 day half-life is probably for 525mg and 700mg.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856743/
It is log scale so hard to estimate, 162mg peak was 6.1 mg/L , So I made lines for 3 and 1.5, look like 4.5 day half-life at that dose. Then 324mg was 13.8 peak, so that is looking like 6.5 day.
So the 10 day half-life is probably for 525mg and 700mg.
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